Mac's don't need defragging as OS X automatically writes 2Gb or below sized files to one contiguous space on the drive. There are certain cases where's it's needed to free up a large spaces on the drive, but not something everyone has to do.
Mac Cleaner enables you to monitor your Mac usage and clean up junk files, unneeded files or large/old files, delete duplicate finders, shred files and uninstall apps from iMac/MacBook to free up much space. Our free virus scanner will find infections on your PC, remove them, and protect you for as long as you need. Got some superbug our free malware removal tool can't handle? Our experts are available 24/7 to help you remove whatever has infected your computer. We'll remotely connect to your computer. Clean and optimize your Mac. Get rid of junk files, duplicates, bad-quality photos, and enjoy all the extra drive space you forgot you had. Rediscover a cleaner, lighter Mac and free up space for your more important files and memories. Our Mac cleaner uses a multilayer system to tune up your. Erase Clutter. Locate and erase unneeded files to save space on your Mac OS. Including iTunes Backup, mail attachment, and multi-languages. Free Mac cleaner with 500 MB. Free try to clean up your Mac. Experience the outstanding features of Mac Cleaner. All kinds of files can be removed. What Mac Cleaner Can Do? There's so much to clean on your Mac, and Mac Cleaner does it for you with one click. It scans everything on your Mac and displays it to you. You can select the items freely and check the scanned results by size, time, etc. It only selects files that are safe-to-delete. So you’re only cleaning up the right files.
Far as other Mac maintainence, there really isn't any except to backup one's files regularly. Keeping Software Updated and run a web browser check to make sure the plug-ins are current.
For Safari and Flash, this check is more accurate What is a dmg file in quickbooks.
Most of those cleaning programs are junk, especially MacKeeper.
If your friend got onto your computer and visited a bunch of adult sites, then I would recommend something like OnyX, doing ALL the cleaning and maintenance aspects and rebooting, perhaps followed by a Disk Utility Erase free space.
CCleaner beta is out for OS X, used on PC's and combines cleaning and scrubbing of the drive if setup correctly.
If your interested in performance, read my post here
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